R. Molife: search on Z-Library

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1

405 A mass balance study to investigate the metabolism, excretion and pharmacokinetics of [14C]-olaparib (AZD2281) in patients with advanced solid tumours refractory to standard treatments

J.E. Ang, J.A. Clarkson-Jones, H. Swaisland, A.T. Brunetto, R. Lal, A.P. Farnsworth, L.R. Molife, S.B. Kaye, J. Carmichael, J.S. de Bono

Journal:

European Journal of Cancer Supplements

Year:

2010

Language:

english

File:

PDF, 65 KB

english, 2010

2

Assessment of Patient-Reported Outcomes of Insulin Pen Devices Versus Conventional Vial and Syringe

Molife, Cliff, Lee, Lauren J., Shi, Lizheng, Sawhney, Monika, Lenox, Sheila M.

Journal:

Diabetes Technology & Therapeutics

Year:

2009

Language:

english

File:

PDF, 115 KB

english, 2009

3

Adjuvant therapy of malignant melanoma

R. Molife, B.W. Hancock

Journal:

Critical Reviews in Oncology/Hematology

Year:

2002

Language:

english

File:

PDF, 230 KB

english, 2002

4

Oestrogenic Steroids and Melanoma Cell Interaction with Adjacent Skin Cells Influence Invasion of Melanoma Cells In Vitro

SHEILA MAC NEIL, PAULA EVES, BEN RICHARDSON, RHODA MOLIFE, PAUL LORIGAN, MARK WAGNER, CHRIS LAYTON, RENATO MORANDINI, GHANEM GHANEM

Journal:

Pigment Cell & Melanoma Research

Year:

2000

Language:

english

File:

PDF, 10.01 MB

english, 2000

5

A phase I dose escalation study of the pharmacokinetics and tolerability of ZK 304709, an oral multi-targeted growth inhibitor (MTGI™), in patients with advanced solid tumours

Edwina N. Scott, Anne L. Thomas, L. Rhoda Molife, Samreen Ahmed, Sarah Blagden, Peter C. Fong, Kristin Kowal, Candice McCoy, Herbert Wiesinger, Will Steward, Johann De Bono

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2009

Language:

english

File:

PDF, 253 KB

english, 2009

6

Pharmacokinetic and pharmacodynamic properties of an oral formulation of the histone deacetylase inhibitor Belinostat (PXD101)

N. L. Steele, J. A. Plumb, L. Vidal, J. Tjørnelund, P. Knoblauch, P. Buhl-Jensen, R. Molife, R. Brown, J. S. de Bono, T. R. J. Evans

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2011

Language:

english

File:

PDF, 298 KB

english, 2011

7

A phase I trial of ispinesib, a kinesin spindle protein inhibitor, with docetaxel in patients with advanced solid tumours

Blagden, S P, Molife, L R, Seebaran, A, Payne, M, Reid, A H M, Protheroe, A S, Vasist, L S, Williams, D D, Bowen, C, Kathman, S J

Journal:

British Journal of Cancer

Year:

2008

Language:

english

File:

PDF, 150 KB

english, 2008

8

A phase I study of the safety and pharmacokinetics of the histone deacetylase inhibitor belinostat administered in combination with carboplatin and/or paclitaxel in patients with solid tumours

Lassen, U, Molife, L R, Sorensen, M, Engelholm, S-A, Vidal, L, Sinha, R, Penson, R T, Buhl-Jensen, P, Crowley, E, Tjornelund, J

Journal:

British Journal of Cancer

Year:

2010

Language:

english

File:

PDF, 316 KB

english, 2010

9

The insulin-like growth factor-I receptor inhibitor figitumumab (CP-751,871) in combination with docetaxel in patients with advanced solid tumours: results of a phase Ib dose-escalation, open-label study

Molife, L R, Fong, P C, Paccagnella, L, Reid, A H M, Shaw, H M, Vidal, L, Arkenau, H-T, Karavasilis, V, Yap, T A, Olmos, D

Journal:

British Journal of Cancer

Year:

2010

Language:

english

File:

PDF, 469 KB

english, 2010

10

FGF Receptor Inhibitors: Role in Cancer Therapy

Gennaro Daniele, Jesus Corral, L. Rhoda Molife, Johann S. de Bono

Journal:

Current Oncology Reports

Year:

2012

Language:

english

File:

PDF, 308 KB

english, 2012

11

Participation of patients with gynecological cancer in phase I clinical trials: Two years experience in a major cancer center

F. Legge, D. Eaton, R. Molife, G. Ferrandina, I. Judson, J. de Bono, S. Kaye

Journal:

Gynecologic Oncology

Year:

2007

Language:

english

File:

PDF, 279 KB

english, 2007

12

A study of the pattern of hospital admissions in a specialist Phase I oncology trials unit: Unplanned admissions as an early indicator of patient attrition

Andre T. Brunetto, Joo Ern Ang, David Olmos, Daniel Tan, Jorge Barriuso, Hendrik-Tobias Arkenau, Timothy A. Yap, L. Rhoda Molife, Udai Banerji, Johann de Bono, Ian Judson, Stan Kaye

Journal:

European Journal of Cancer

Year:

2010

Language:

english

File:

PDF, 188 KB

english, 2010

13

1202 ORAL A Phase I Study of the Potent AKT Inhibitor MK-2206 in Combination With Carboplatin and Paclitaxel, Docetaxel or Erlotinib in Patients With Advanced Solid Tumours

L.R. Molife, S. Minton, J. Vitfell-Pedersen, E. Chen, D. Sullivan, L. Yan, A.M. Zernhelt, L. Siu, J.S. de Bono, A.W. Tolcher

Journal:

European Journal of Cancer

Year:

2011

Language:

english

File:

PDF, 64 KB

english, 2011

14

1232 POSTER Creatinine Clearance (CrCI) as a Predictive Marker for the Risk of Toxicity From Molecularly Targeted Agents (MTA) in Phase I Trials

J. Vitfell-Pedersen, B. Basu, V. Moreno, A. Tjokrowidjaja, M. Puglisi, K. Shah, S. Malvankar, S. Alam, R. Molife, U. Banerji

Journal:

European Journal of Cancer

Year:

2011

Language:

english

File:

PDF, 46 KB

english, 2011

15

Safety, pharmacokinetics, and preliminary activity of the anti-IGF-1R antibody figitumumab (CP-751,871) in patients with sarcoma and Ewing's sarcoma: a phase 1 expansion cohort study

David Olmos, Sophie Postel-Vinay, L Rhoda Molife, Scott H Okuno, Scott M Schuetze, M Luisa Paccagnella, Gretchen N Batzel, Donghua Yin, Kathryn Pritchard-Jones, Ian Judson, Francis P Worden, Antonio G

Journal:

The Lancet Oncology

Year:

2010

Language:

english

File:

PDF, 398 KB

english, 2010

16

Gender and survival in malignant tumours

R. Molife, P. Lorigan, S. MacNeil

Journal:

Cancer Treatment Reviews

Year:

2001

Language:

english

File:

PDF, 83 KB

english, 2001

17

Association of creatine kinase and skin toxicity in phase I trials of anticancer agents

Moreno Garcia, V, Thavasu, P, Blanco Codesido, M, Molife, L R, Vitfell Pedersen, J, Puglisi, M, Basu, B, Shah, K, Iqbal, J, de Bono, J S, Kaye, S B, Banerji, U

Journal:

British Journal of Cancer

Year:

2012

Language:

english

File:

PDF, 580 KB

english, 2012

18

PDB61 PREDICTORS OF INSULIN DELIVERY SYSTEM USE IN PATIENTS WITH TYPE 2 DIABETES

C Molife, RP Hayes

Journal:

Value in Health

Year:

2008

Language:

english

File:

PDF, 68 KB

english, 2008

19

196 POSTER A phase I trial incorporating the pharmacodynamic (PD) study of circulating tumour cells (CTC) of CP-751,871 (C), a monoclonal antibody against the insulin-like growth factor 1 receptor (IGF-1R), in combination with docetaxel (D) in patients (p) with advanced cancer

P.C. Fong, R.L. Molife, J. Spicer, T.A. Yap, S. Settatree, L. Digue, G. Attard, V. Karavasilis, A. Gualberto, J.S. de Bono

Journal:

European Journal of Cancer Supplements

Year:

2006

Language:

english

File:

PDF, 71 KB

english, 2006

20

357 POSTER A phase I safety, pharmacokinetic and pharmacodynamic study of intravenously administered PXD101 plus carboplatin or paclitaxel or both in patients with advanced solid tumors

U. Lassen, M. Sørensen, J.S. De Bono, R. Molife, L. Vidal, S. Settatree, M.V. Seiden, S.X. Li, P.B. Jensen

Journal:

European Journal of Cancer Supplements

Year:

2006

Language:

english

File:

PDF, 59 KB

english, 2006

21

Secondary mutations in BRCA2 associated with clinical resistance to a PARP inhibitor

Barber, Louise J, Sandhu, Shahneen, Chen, Lina, Campbell, James, Kozarewa, Iwanka, Fenwick, Kerry, Assiotis, Ioannis, Rodrigues, Daniel Nava, Reis-Filho, Jorge S, Moreno, Victor, Mateo, Joaquin, Molif

Journal:

The Journal of Pathology

Year:

2013

Language:

english

File:

PDF, 499 KB

english, 2013

22

PCV135 Low Lipoprotein Cholesterol Goal Attainment in Dyslipidemic Patients with Existing Statin therapy: A Chart Extraction-Based Approach

J. Ivanova, C. Frois, J.P. Bae, S.D. Boykin, R. Mccracken, C. Molife, T. Waldman, Z. Zhao

Journal:

Value in Health

Year:

2011

Language:

english

File:

PDF, 59 KB

english, 2011

23

PCV136 Factors Associated with Failing to Achieve Low Density Lipoprotein Cholesterol Goal with Existing Statin Therapy: A Chart Extraction-Based Approach

Z. Zhao, J. Ivanova, J.P. Bae, S.D. Boykin, R. Mccracken, C. Molife, T. Waldman, C. Frois

Journal:

Value in Health

Year:

2011

Language:

english

File:

PDF, 59 KB

english, 2011

24

PCV134 Concomitant Medciation Use in US Adults on Statin Therapy: Findings from a Multi-Employer Claims Database

C. Molife, Y. Zhu, C. Yu, R. Mccracken, Z. Zhao

Journal:

Value in Health

Year:

2011

Language:

english

File:

PDF, 70 KB

english, 2011

25

MA1 Medication Adherence and Persistence of Prasugrel Initiators Post ACS-PCI

J.C. Simeone, B. Nordstrom, Z. Zhao, C. Molife, P.L. Mccollam, X. Ye, M.B. Effron

Journal:

Value in Health

Year:

2012

Language:

english

File:

PDF, 58 KB

english, 2012

26

PCV21 Patient Characteristics and Dosage Patterns of Statin Users in Japan: A Health Care Database Analysis

Z. Zhao, Y. Zhu, P.L. McCollam, C. Molife, C.A. Sponseller, V. Kryzhanovski

Journal:

Value in Health

Year:

2012

Language:

english

File:

PDF, 59 KB

english, 2012

27

PCV118 Characteristics of Patients Treated with Thienopyridines Following ACS-PCI

B. Nordstrom, J.C. Simeone, Z. Zhao, C. Molife, P.L. Mccollam, X. Ye, M.B. Effron

Journal:

Value in Health

Year:

2012

Language:

english

File:

PDF, 70 KB

english, 2012

28

26 INVITED Selective CYP17 inhibition with abiraterone acetate (AA) in castration resistant prostate cancer (CRPC): the Royal Marsden Hospital experience

A. Reid, G. Attard, N. Babu Oommen, D. Olmos, P. Fong, R. Molife, M. Dowsett, G. Lee, A. Molina, J.S. De-Bono

Journal:

European Journal of Cancer Supplements

Year:

2008

Language:

english

File:

PDF, 61 KB

english, 2008

29

1257 Retrospective analysis of unplanned hospital admissions: an early surrogate indicator of patient (pt) attrition in phase-I trials

D. Olmos, A. Brunetto, J. Ang, D. Tan, S. Sandhu, R. Kristeleit, M. Lolkelma, M. Forster, R. Molife, S. Kaye

Journal:

European Journal of Cancer Supplements

Year:

2009

Language:

english

File:

PDF, 70 KB

english, 2009

30

449 Increased levels of serum creatine kinase caused by skin toxicity of molecularly targeted anticancer agents in phase 1 clinical trials

V. Moreno Garcia, R. Molife, J. Pedersen, M. Puglisi, M. Blanco, B. Basu, K. Shah, U. Banerji

Journal:

European Journal of Cancer Supplements

Year:

2010

Language:

english

File:

PDF, 44 KB

english, 2010

31

Treatment with olaparib in a patient with PTEN-deficient endometrioid endometrial cancer

Forster, Martin D., Dedes, Konstantin J., Sandhu, Shahneen, Frentzas, Sophia, Kristeleit, Rebecca, Ashworth, Alan, Poole, Christopher J., Weigelt, Britta, Kaye, Stan B., Molife, L. Rhoda

Journal:

Nature Reviews Clinical Oncology (formerly Nature Clinical Practice Oncology)

Year:

2011

Language:

english

File:

PDF, 1.21 MB

english, 2011

32

Phase I trials in patients with relapsed, advanced upper gastrointestinal carcinomas: experience in a specialist unit

Khan, Khurum, Ang, Joo Ern, Starling, Naureen, Sclafani, Francesco, Shah, Krunal, Judson, Ian, Molife, L. Rhoda, Banerji, Udai, de Bono, Johann S., Cunningham, David, Kaye, Stan B.

Journal:

Year:

2014

Language:

english

File:

PDF, 250 KB

english, 2014

33

Phase 1 trial of the oral AKT inhibitor MK-2206 plus carboplatin/paclitaxel, docetaxel, or erlotinib in patients with advanced solid tumors

L Rhoda Molife,Li Yan,Joanna Vitfell-Rasmussen…

Journal:

Journal of Hematology & Oncology

Year:

2014

Language:

english

File:

PDF, 389 KB

english, 2014

34

Phase II, open-label trial to assess QTcF effects, pharmacokinetics and antitumor activity of afatinib in patients with relapsed or refractory solid tumors

Molife, L. Rhoda, Rudman, Sarah M., Alam, Salma, Tan, Daniel S.-W., Kristeleit, Hartmut, Middleton, Gary, Propper, David, Bent, Liz, Stopfer, Peter, Uttenreuther-Fischer, Martina, Wallenstein, Gudrun,

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2013

Language:

english

File:

PDF, 697 KB

english, 2013

35

Adherence and Persistence with Prasugrel Following Acute Coronary Syndrome with Percutaneous Coronary Intervention

Nordstrom, Beth L., Simeone, Jason C., Zhao, Zhenxiang, Molife, Cliff, McCollam, Patrick L., Ye, Xin, Effron, Mark B.

Journal:

American Journal of Cardiovascular Drugs

Year:

2013

Language:

english

File:

PDF, 306 KB

english, 2013

36

Cancer therapeutics: Targeting the apoptotic pathway

Khan, Khurum H., Blanco-Codesido, Montserrat, Molife, L. Rhoda

Journal:

Critical Reviews in Oncology/Hematology

Year:

2014

Language:

english

File:

PDF, 2.75 MB

english, 2014

37

DIFFERENTIAL USE BETWEEN PRASUGREL AND TICAGRELOR IN PATIENTS WITH ACUTE CORONARY SYNDROME UNDERGOING PERCUTANEOUS CORONARY INTERVENTION IN ROUTINE PRACTICE

Effron, Mark B., Molife, Cliff, Karkare, Swapna, Larmore, Cynthia, Zhu, Yajun, Lee, Won Chan, Frech-Tamas, Feride, Lieu, Hsiao, DeKoven, Mitch

Journal:

Journal of the American College of Cardiology

Year:

2014

Language:

english

File:

PDF, 462 KB

english, 2014

38

Safety, tolerability and anti-tumour activity of the androgen biosynthesis inhibitor ASP9521 in patients with metastatic castration-resistant prostate cancer: multi-centre phase I/II study

Loriot, Yohann, Fizazi, Karim, Jones, Robert J., Van den Brande, Jan, Molife, Rhoda L., Omlin, Aurelius, James, Nicholas D., Baskin-Bey, Edwina, Heeringa, Marten, Baron, Benoit, Holtkamp, Gertjan M.,

Journal:

Investigational New Drugs

Year:

2014

Language:

english

File:

PDF, 1000 KB

english, 2014

39

Targeting the insulin-like growth factor signaling pathway: figitumumab and other novel anticancer strategies

Yap, Timothy A, Olmos, David, Molife, Lulama Rhoda, de Bono, Johann S

Journal:

Expert Opinion on Investigational Drugs

Year:

2011

Language:

english

File:

PDF, 515 KB

english, 2011

40

Phase II study of docetaxel in patients with relapsed or refractory malignant lymphoma

Zekri, J M, Hough, R E, Davies, J M, Molife, R, Hancock, B W, Lorigan, P C

Journal:

British Journal of Cancer

Year:

2003

Language:

english

File:

PDF, 83 KB

english, 2003

41

Improving the outcome of patients with castration-resistant prostate cancer through rational drug development

Attard, G, Sarker, D, Reid, A, Molife, R, Parker, C, de Bono, J S

Journal:

British Journal of Cancer

Year:

2006

Language:

english

File:

PDF, 136 KB

english, 2006

42

A Phase I Pharmacokinetic and Pharmacodynamic Study of TKI258, an Oral, Multitargeted Receptor Tyrosine Kinase Inhibitor in Patients with Advanced Solid Tumors

Sarker, D., Molife, R., Evans, T.R. J., Hardie, M., Marriott, C., Butzberger-Zimmerli, P., Morrison, R., Fox, J. A., Heise, C., Louie, S., Aziz, N., Garzon, F., Michelson, G., Judson, I. R., Jadayel,

Journal:

Clinical Cancer Research

Year:

2008

Language:

english

File:

PDF, 575 KB

english, 2008

43

Selective Inhibition of CYP17 With Abiraterone Acetate Is Highly Active in the Treatment of Castration-Resistant Prostate Cancer

Attard, G., Reid, A. H.M., A'Hern, R., Parker, C., Oommen, N. B., Folkerd, E., Messiou, C., Molife, L. R., Maier, G., Thompson, E., Olmos, D., Sinha, R., Lee, G., Dowsett, M., Kaye, S. B., Dearnaley,

Journal:

Journal of Clinical Oncology

Year:

2009

Language:

english

File:

PDF, 656 KB

english, 2009

44

Toward a Better Dialogue Between Neuro-Oncologists and Phase I Investigators

Massard, C., Sandhu, S., Blanco, M., Papadatos-Pastos, D., Carden, C., De Bono, J., Saran, F., Molife, L. R., Kaye, S. B., Soria, J.-C., Banerji, U.

Journal:

Journal of Clinical Oncology

Year:

2012

Language:

english

File:

PDF, 60 KB

english, 2012

45

Phase I Trials of Molecularly Targeted Agents: Should We Pay More Attention to Late Toxicities?

Postel-Vinay, S., Gomez-Roca, C., Molife, L. R., Anghan, B., Levy, A., Judson, I., De Bono, J., Soria, J.-C., Kaye, S., Paoletti, X.

Journal:

Journal of Clinical Oncology

Year:

2011

Language:

english

File:

PDF, 169 KB

english, 2011

46

Phase I Dose Escalation Study of the Anti Insulin-Like Growth Factor-I Receptor Monoclonal Antibody CP-751,871 in Patients with Refractory Solid Tumors

Haluska, P., Shaw, H. M., Batzel, G. N., Yin, D., Molina, J. R., Molife, L. R., Yap, T. A., Roberts, M. L., Sharma, A., Gualberto, A., Adjei, A. A., de Bono, J. S.

Journal:

Clinical Cancer Research

Year:

2007

Language:

english

File:

PDF, 448 KB

english, 2007

47

A Phase I, Dose-Escalation Study of the Multitargeted Receptor Tyrosine Kinase Inhibitor, Golvatinib, in Patients with Advanced Solid Tumors

Molife, L. R., Dean, E. J., Blanco-Codesido, M., Krebs, M. G., Brunetto, A. T., Greystoke, A. P., Daniele, G., Lee, L., Kuznetsov, G., Myint, K. T., Wood, K., de las Heras, B., Ranson, M. R.

Journal:

Clinical Cancer Research

Year:

2014

Language:

english

File:

PDF, 1.07 MB

english, 2014

48

Combining Antiangiogenics to Overcome Resistance: Rationale and Clinical Experience

Moreno Garcia, V., Basu, B., Molife, L. R., Kaye, S. B.

Journal:

Clinical Cancer Research

Year:

2012

Language:

english

File:

PDF, 589 KB

english, 2012

49

Higher Risk of Infections with PI3K-AKT-mTOR Pathway Inhibitors in Patients with Advanced Solid Tumors on Phase I Clinical Trials

Rafii, S., Roda, D., Geuna, E., Jimenez, B., Rihawi, K., Capelan, M., Yap, T. A., Molife, L. R., Kaye, S. B., de Bono, J. S., Banerji, U.

Journal:

Clinical Cancer Research

Year:

2015

Language:

english

File:

PDF, 317 KB

english, 2015

50

HDAC Inhibitors and Cardiac Safety

Molife, R., Fong, P., Scurr, M., Judson, I., Kaye, S., de Bono, J.

Journal:

Clinical Cancer Research

Year:

2007

Language:

english

File:

PDF, 35 KB

english, 2007

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